If retatrutide were available today at the same price as tirzepatide, would you switch? The extra ~2% weight loss doesn't seem worth the unknown long-term safety profile. But the glucagon receptor agonism might help with metabolic health beyond just weight.
Retatrutide vs tirzepatide — which would you choose?
The glucagon receptor adds hepatic fat oxidation which could address fatty liver disease — something tirzepatide doesn't directly do. For metabolic syndrome patients, retatrutide could be superior.
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