BPC 157 and Standard Angiogenic Growth Factors. Gastrointestinal Tract Healing, Lessons from Tendon, Ligament, Muscle and Bone Healing

Authors: Seiwerth S, Rucman R, Turkovic B, Sever M, Klicek R, et al.

Journal
Curr Pharm Des
Year
2018
Citations
160
Type
Review
Subject
Human
Condition
Wound Healing / Tissue Repair
TL;DR

Review examining BPC 157's role in angiogenic healing across gastrointestinal and extragastrointestinal tissues compared to standard growth factors (EGF, FGF, VEGF).

View Paper DOI: 10.2174/1381612824666180712110447

Abstract

Commonly, the angiogenic growth factors signify healing.. However, gastrointestinal ulceration is still poorly understood particularly with respect to a general pharmacological/pathophysiological role of various angiogenic growth factors implemented in growth factors wound healing concept.. Thereby, we focused on the stable gastric pentadecapeptide BPC 157, a peptide given always alone vs.

Key Findings

standard peptidergic angiogenic growth factors (EGF, FGF, VEGF), and numerous carriers. | Further, we reviewed how the gastrointestinal tract healing could be generally perceived (i) in terms of angiogenic growth factors, and/or (ii) through the healing of extragastrointestinal tissues hea... | Respec

Study Design

Review article