The role of mechano-growth factor E peptide in the regulation of osteosarcoma

Abstract

Osteosarcoma is one of the most common bone tumors, and exhibits a high degree of malignancy.. Gene therapy is a novel approach to its treatment, however, specific target genes are required to enable effective use of this therapy.. In order to investigate the effects of the mechano-growth factor E (MGF-E) peptide, which is derived from the IGF-I alternative splicing isoform, on the regulation of.

Key Findings

Gene therapy is a novel approach to its treatment, however, specific target genes are required to enable effective use of this therapy. | In order to investigate the effects of the mechano-growth factor E (MGF-E) peptide, which is derived from the IGF-I alternative splicing isoform, on the regulation of the development of osteosarcoma, ... | The results demonstrated that MGF was overexpressed in malignant osteosarcoma cells, while it was not expressed in the least mal

Study Design

In vitro study