PepsReview

Recent activity

2026-10-06 21:56 in 48-week 24.2% vs Phase 3 28.7% — what gives?

One thing I’d pull from older trial threads: baseline weight/BMI and diabetes mix. A 300-lb cohort losing 24% is 72 lb; a 240-lb cohort losi…

2026-10-06 00:12 in Four months on nights, down two scrubs sizes

One thing that surprised me on nights: my hunger curve shifted hard toward the end of shift. In the trials, circadian misalignment tends to …