Wegovy Dosage Chart 2026: Approved Schedule, Pen Strengths, and Missed-Dose Rules

The complete Wegovy (semaglutide 2.4 mg) titration schedule: all five pen strengths, the weekly escalation ladder, what to do about missed doses, and how brand-name dosing maps to the compound calculators.

The Approved Titration Schedule

Wegovy is semaglutide at weight-management dosing: one weekly subcutaneous injection following a five-step titration — 0.25 mg for weeks 1-4 (initiation), 0.5 mg for weeks 5-8, 1.0 mg for weeks 9-12, 1.7 mg for weeks 13-16, and 2.4 mg from week 17 onward as the target maintenance dose. The ladder exists for tolerability: nausea and GI effects concentrate in the escalation weeks, and the slow steps let the body adapt. The same molecule is Ozempic at diabetes dosing (0.25-2.0 mg) — the "what are the doses of Wegovy" question is answered by the weight-management schedule above. Our semaglutide calculator encodes the same ladder for protocol math on the research side.

Pen Strengths and Delivery Math

Wegovy ships in five pen strengths matching the schedule: 0.25 mg, 0.5 mg, 1.0 mg, 1.7 mg, and 2.4 mg per injection, each pen delivering four weekly doses. The delivery math matters for two practical reasons: pens are single-patient and single-dose (no multi-dose draws), and the titration schedule means the first months use lower-strength pens that are not interchangeable with later ones. For anyone comparing costs, the per-month price is the same across strengths — the number that changes is total treatment duration. Our GLP-1 cost comparison covers price-per-mg across programs; our insurance calculator models what coverage does to the cash price.

Missed Doses and Scheduling Rules

The label rule for missed doses: if one weekly dose is missed and the next scheduled dose is more than 48 hours away, take it as soon as remembered; if less than 48 hours remain, skip and resume on schedule. After two consecutive missed doses, the guidance is to contact the prescribing provider about restarting titration — potentially back at a lower step. The half-life (about one week) is what makes the schedule forgiving, and it is also why steady-state takes 4-5 weeks to establish at each new dose. The same logic appears in our semaglutide reconstitution guide for research contexts — weekly molecules accumulate, so escalation math compounds.

Wegovy vs the Alternatives

Wegovy (2.4 mg semaglutide, ~15% trial weight loss) sits in the middle of the efficacy ladder: tirzepatide/Zepbound leads among approved options (22.5% in SURMOUNT-1), retatrutide leads all trial data (up to 31%, investigational), and oral orforglipron now offers the needle-free route at the convenience tier. The semaglutide shortage that opened the compounding window has ended — the FDA closed compounded copies of Wegovy, a shift we covered as it happened. For research math on all of these, the calculators encode each molecule's ladder; for brand costs, the cost comparison tracks list prices and program pricing side by side.

📊 Dosage Calculator & Protocol Chart

Use our free Wegovy dosage calculator to plan your protocol:

👉 Wegovy Dosage Calculator — Calculate exact dosing, reconstitution ratios, and injection volumes.

👉 Full Dosing Guide & Protocol Chart — Complete protocol with weekly titration schedule, side effect management, and cycle recommendations.

Important Disclaimer

This article is for educational and research purposes only. Peptides discussed may not be FDA-approved for all uses described. Always consult with a qualified healthcare provider before starting any peptide protocol. The information provided here is synthesized from published research, clinical trial data, and community discussions.

Keywords: wegovy dosage chart, wegovy doses, wegovy titration, semaglutide dosage chart, wegovy pen doses, wegovy pill

Sources: Published research papers, clinical trial databases, community discussions, peptiq.io educational content