Switching from semaglutide to tirzepatide — my 2-week experience

2026-09-03 236 views 3 posts

Was on sema for 11 months, hit a wall, switched to tirz 10 weeks ago. The difference is noticeable. Better appetite suppression, fewer side effects, more consistent energy. Down 34 lbs since switching. Anyone else made this switch? Curious about long-term differences.

My doctor had me split the dose — half on Monday, half on Thursday. Helped with the nausea significantly. Might be worth asking your doctor about.

I've been at 10mg for 2 months now. The jump from 5 to 10 was noticeable — more appetite suppression but also more nausea for the first two weeks. It settled down after that. I'd say go for it if you're stalling at the current dose.