tirzepatide 7.5 mg, injection day 3, and I spent four hours cycling between cramps and watery stools. No fever, no blood, no travel or novel food.
I had loperamide in the cabinet but didn't take it; I was more worried about stacking a slowing GI agent on top of delayed gastric emptying than about the diarrhea itself. My nurse line's triage focused on hydration, electrolytes, and red flags, but didn't give me a blanket yes/no on OTC antidiarrheals.
For those who've asked this of a prescriber or pharmacist: how did they frame the risk? Did anyone get a clear 'avoid unless X' versus 'fine for short-term symptom control'?
Not looking for dosing guidance, just trying to understand the clinical reasoning.