CJC-1295

GHRH analog — extends natural growth hormone pulse duration

3.5
2 avis

Rating Breakdown

GH Release Potency
4.0
IGF-1 Elevation
3.5
Muscle Preservation
3.5
Fat Loss Support
2.5
Sleep Quality Improvement
4.5
Safety & Side Effects
4.0
Anti-Aging Effect
3.5
Cost Effectiveness
3.5

Aperçu

CJC-1295 is a modified version of growth hormone releasing hormone (GHRH) that extends the half-life to ~30 minutes and increases GH pulse amplitude.

Key Information

Identity
Also Known As Modified GRF(1-29)
Sequence Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Phe-Val-Lys-Trp-Ala-Mod
CAS Number 863288-80-8
Molecular Formula C58H84N14O13
Properties
Half-Life 30 minutes (no DAC), 8 days (DAC)
Administration subcutaneous injection
Dosage Range 100-300 mcg daily
Price Range $0.7–$5.0/mg
Handling & Storage
Storage Lyophilized: -20C; Reconstituted: 2-8C
Reconstitution Reconstitute with bacteriostatic water
Regulatory Status
US Status Research only
Legal Status Not FDA-approved. Available as research chemical.
Research Papers 1 indexed

Mechanism

Binds to GHRH receptors in the pituitary to enhance natural GH pulse frequency and amplitude. Often paired with a GHRP like Ipamorelin.

Benefits

  • Extended GH release
  • Increased IGF-1
  • Improved sleep quality
  • Anti-aging potential

Side Effects

  • Water retention
  • Mild flushing
  • Paresthesia

Contraindications

  • Active cancer
  • Pregnancy

Evidence Summary

Studies show 2-10x increase in GH levels.

Research

Studies show 2-10x increase in GH levels. DAC variant extends half-life to 8 days.

View Research

Safety

Generally well-tolerated. Water retention possible at high doses.

Legal Status

Not FDA-approved. Available as research chemical.

Recherche

1 research papers indexed

View Research

Write a Review

Rating Breakdown

Effectiveness
4.0
Safety
4.0
Value
3.5
Overall
3.5

Based on 2 avis.

Avis

Subtle effects, expensive 2026-05-27
Hannah V.

Used CJC-1295 for 8 weeks. Sleep improved but the body composition changes were subtle. Better stacked with a GHRP. The DAC version lasts longer but water retention can be an issue.

Effectiveness: 4/5 Safety: 4/5 Value: 3/5
Better sleep and recovery 2026-05-07
Hannah V.

CJC-1295 with DAC improved my sleep quality significantly. Deeper sleep, better recovery. Noticeable body composition changes over 3 months - leaner while maintaining muscle. IGF-1 increase is real.

Effectiveness: 4/5 Safety: 4/5 Value: 4/5