Retatrutide vs tirzepatide — my 7-month comparison

2026-09-07 224 views 5 posts

Was on tirz for 21 months, switched to retta 8 months ago. Here's my honest comparison: retta gives me more energy, slightly more nausea, and faster weight loss. Down 11 on retta vs 22 on tirz in the same timeframe. The triple agonist mechanism really seems to make a difference for me.

I could have written this post. Down 45 lbs in a similar timeframe. The mental shift is bigger than the physical one, honestly. I feel like a different person.

This is so relatable. I'm on week 7 and feeling the same way. The food noise disappearing was the most surprising part for me too. I didn't even know I had it until it was gone.

I switched from sema to tirz about 3 months ago. Big improvement in appetite suppression and fewer side effects. Down 15 lbs since switching. Everyone's different but for me it was the right call.

Same here! I had the exact same experience at 12.5mg. The nausea peaked around week 1 and then gradually improved. Hang in there, it gets better.