GLP-1 Medications 2026: The Complete List, Best Options, and Cheapest Prices
Every GLP-1 receptor agonist tracked by researchers in 2026 — semaglutide, tirzepatide, retatrutide, liraglutide, survodutide and the oral candidates — with titration ladders, efficacy numbers, and price-per-mg comparisons in one reference list.
The Complete GLP-1 List
The GLP-1 receptor agonist class has split into three tiers. Approved injectables: semaglutide (Wegovy, Ozempic), tirzepatide (Zepbound, Mounjaro), liraglutide (Saxenda, Victoza), and dulaglutide. Investigational injectables: retatrutide — the triple agonist that posted 31% mean weight loss in Phase 3 (TRIUMPH-4: 71.2 lbs from a 248.5 lb baseline over 68 weeks at 12 mg) — plus survodutide and cagrisema, the amylin-GLP-1 combination. Oral candidates: orforglipron, the first FDA-approved oral GLP-1 for weight loss, and oral semaglutide (Rybelsus). Each compound has a distinct titration schedule; our per-peptide calculators encode the clinical ladders so you can check the math yourself.
Which GLP-1 Is "Best" in 2026?
By efficacy, the ordering is clear from trial data: retatrutide (up to 31% mean weight loss) leads every published trial result in the class, ahead of tirzepatide (22.5% in SURMOUNT-1) and semaglutide (15% in STEP-1). But "best" depends on context. For glycemic control in type 2 diabetes, semaglutide and tirzepatide have the deepest outcome datasets. For convenience, the newly approved oral orforglipron removes refrigeration and injections entirely. For budget research, generic liraglutide remains the cheapest approved injectable, and we maintain a live price-per-mg comparison across programs. Retatrutide remains investigational in 2026 — Phase 3 readouts are approaching but it is not FDA-approved.
The Cheapest GLP-1 Options
Cost divides the class sharply. Brand programs run $500-$1,350 per month at list price. Compounded semaglutide from telehealth clinics runs $150-$300 per month but exists only under shortage-era rules that the FDA has been narrowing since the semaglutide shortage ended. Our price-per-mg tracker shows generic liraglutide as the low-cost approved option, while orforglipron is expected to undercut injectable pricing because small-molecule manufacturing scales like conventional pharmaceuticals. Check the linked cost comparison for live numbers before assuming the sticker price is what you would pay.
How to Compare Programs Safely
Whichever program you compare, three checks matter more than the headline price: confirm the compound and dose per vial (25 mg vials vs 5 mg vials change the per-mg math), confirm COA availability from an independent lab for anything compounded, and confirm the titration schedule matches the clinical ladder rather than an aggressive shortcut. Our vendor COA-verification guide walks through reading a certificate of analysis, and our GLP-1 insurance calculator estimates what coverage would apply to approved options. The GLP-1 market is now the most counterfeited drug category in the world — the green-list and counterfeit API stories we track in our news section are not theoretical.
📊 Dosage Calculator & Protocol Chart
Use our free GLP-1 dosage calculator to plan your protocol:
👉 GLP-1 Dosage Calculator — Calculate exact dosing, reconstitution ratios, and injection volumes.
👉 Full Dosing Guide & Protocol Chart — Complete protocol with weekly titration schedule, side effect management, and cycle recommendations.
Important Disclaimer
This article is for educational and research purposes only. Peptides discussed may not be FDA-approved for all uses described. Always consult with a qualified healthcare provider before starting any peptide protocol. The information provided here is synthesized from published research, clinical trial data, and community discussions.
Keywords: glp-1 medications, glp-1 list, best glp-1 for weight loss, cheapest glp-1, glp-1 agonist list, glp 1 meds list
Sources: Published research papers, clinical trial databases, community discussions, peptiq.io educational content