Growth hormone releasing hormone
Autores: Grossman A, Savage MO, Besser GM
Revista
Clin Endocrinol Metab
Año
1986
Citas
800
Type
Animal Study
Subject
Human
Condition
Growth Hormone Deficiency
TL;DR
Review of GHRH: a 44-residue peptide that specifically increases circulating GH across species and may promote long-term growth, with ~70% human-rat homology.
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DOI: 10.1016/s0300-595x(86)80012-3
Abstract
Human growth hormone releasing hormone (GHRH) was originally extracted from two pancreatic tumours in patients with acromegaly, and is now known to consist of a 44 residue amidated peptide or its C-terminal-shortened derivatives.. The sequence of rat GHRH has also been determined; this 43 residue peptide shows approximately 70% homology with human GHRH, and is located mainly in the arcuate.