Identification of CJC-1295, a growth-hormone-releasing peptide, in an unknown pharmaceutical preparation

Autores: Henninge J, Pepaj M, Hullstein I, Hemmersbach P

Revista
Drug Test Anal
Año
2010
Citas
320
Type
Research Article
Subject
Human
Condition
Growth Hormone Deficiency
TL;DR

Norwegian police/customs analysis identified CJC-1295 (29-amino-acid GHRH analog) in an unknown pharmaceutical preparation using mass spectrometry.

Ver Artículo DOI: 10.1002/dta.233

Abstract

Several peptide drugs are being manufactured illicitly, and in some cases they are being made available to the public before entering or completing clinical trials.. At the request of Norwegian police and customs authorities, unknown pharmaceutical preparations suspected to contain peptide drugs are regularly subjected to analysis.. In 2009, an unknown pharmaceutical preparation was submitted for.

Hallazgos Clave

The preparation was found to contain a 29 amino acid peptide with a C-terminal amide function. | Based on the interpretation of mass spectrometric data, an amino acid sequence was proposed. | The sequence is consistent with a peptide currently marketed under the name

Diseño del Estudio

Clinical study