Identification of CJC-1295, a growth-hormone-releasing peptide, in an unknown pharmaceutical preparation

Authors: Henninge J, Pepaj M, Hullstein I, Hemmersbach P

Journal
Drug Test Anal
Year
2010
Citations
320
Type
Research Article
Subject
Human
Condition
Growth Hormone Deficiency
TL;DR

Norwegian police/customs analysis identified CJC-1295 (29-amino-acid GHRH analog) in an unknown pharmaceutical preparation using mass spectrometry.

View Paper DOI: 10.1002/dta.233

Abstract

Several peptide drugs are being manufactured illicitly, and in some cases they are being made available to the public before entering or completing clinical trials.. At the request of Norwegian police and customs authorities, unknown pharmaceutical preparations suspected to contain peptide drugs are regularly subjected to analysis.. In 2009, an unknown pharmaceutical preparation was submitted for.

Key Findings

The preparation was found to contain a 29 amino acid peptide with a C-terminal amide function. | Based on the interpretation of mass spectrometric data, an amino acid sequence was proposed. | The sequence is consistent with a peptide currently marketed under the name

Study Design

Clinical study