Ipamorelin
Selective GHRP — releases growth hormone without hunger side effects
Overview
Ipamorelin is a growth hormone secretagogue that stimulates the release of natural growth hormone without the hunger side effects common to other GHRPs.
Key Information
Mechanism
Agonizes ghrelin receptors in the pituitary to stimulate GH release. Does not significantly increase cortisol, prolactin, or ACTH.
Benefits
- Stimulates GH release
- Minimal hunger side effects
- No cortisol impact
- Selective GH secretagogue
Side Effects
- Mild headache
- Flushing
- Water retention
Contraindications
- Active cancer
- Pregnancy
Evidence Summary
Studies show effective GH release with minimal side effects.
Research
Studies show effective GH release with minimal side effects. Often combined with CJC-1295 for synergistic effect.
View ResearchSafety
Well-tolerated. Minimal impact on other hormones compared to GHRP-2/6.
Frequently Asked Questions About Ipamorelin
What is Ipamorelin?
Ipamorelin is a research peptide also known as Growth hormone secretagogue. Selective GHRP — releases growth hormone without hunger side effects It is studied for its potential therapeutic applications and is available from various research chemical vendors.
How does Ipamorelin work?
Agonizes ghrelin receptors in the pituitary to stimulate GH release. Does not significantly increase cortisol, prolactin, or ACTH.
What is the recommended dosage for Ipamorelin?
The commonly studied dosage range for Ipamorelin is 200-300 mcg, 2-3x daily. Dosage protocols vary based on research objectives. Always consult published studies and start with conservative amounts. Ipamorelin should only be used in controlled research settings.
Where can I buy Ipamorelin?
PepsReview indexes Ipamorelin pricing from multiple vendors. Check the Vendors tab above for a price comparison table showing cost per milligram, purity, COA status, and stock availability. Vendor reviews from real users are available on each vendor's profile page.
Is Ipamorelin legal?
US regulatory status: Research only. The legal status of Ipamorelin varies by jurisdiction. In most countries, it is sold as a research chemical, not for human consumption. Always verify the legal status in your country before purchasing.
What are the side effects of Ipamorelin?
Reported side effects include: Mild headache, Flushing, Water retention. Always review safety data and published studies before use.
Key Research Papers on Ipamorelin
The following peer-reviewed studies and clinical trials are indexed in our research library for Ipamorelin. Each paper links to a detailed summary with key findings, study design, and publication metadata.
- Ipamorelin, the first selective growth hormone secretagogue — Eur J Endocrinol, 1998 (560 citations)
- Ipamorelin, a new growth-hormone-releasing peptide, induces longitudinal bone growth in rats — Growth Horm IGF Res, 1999 (540 citations)
- Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers — Pharm Res, 1999 (540 citations)
- Highly potent growth hormone secretagogues: hybrids of NN703 and ipamorelin — Bioorg Med Chem Lett, 2001 (500 citations)
- The growth hormone secretagogue receptor 1a agonists, anamorelin and ipamorelin, inhibit cisplatin-induced weight loss in ferrets: Anamorelin also exhibits anti-emetic effects via a central mechanism — Physiol Behav, 2024 (40 citations)
Related Growth hormone boosters Peptides
Other peptides in the growth hormone boosters category that may be of interest for comparative research:
Write a Review
Rating Breakdown
Based on 2 reviews.
Reviews
Stacked ipamorelin with CJC-1295 (no DAC). Synergy is real - best sleep of my life, skin improved, fat loss accelerated. No hunger or cortisol issues. The most selective GH secretagogue available.
Ipamorelin is the cleanest GHRP I've used. No hunger spike like GHRP-6, no cortisol impact. GH pulse is steady. Sleep improved, recovery faster. Best for those sensitive to side effects.