Investigación: Epithalon

Telomerase activator — anti-aging and longevity peptide

Epithalon Research Papers & Clinical Studies

Epithalon is a peptide studied for its potential therapeutic effects. Telomerase activator — anti-aging and longevity peptide This page indexes all published research papers, clinical trials, and scientific studies related to Epithalon that are available in the PepsReview research library. Each paper includes metadata such as journal name, publication year, citation count, study type, and a summary of key findings. Where available, we provide direct links to the original publication and DOI references.

Researchers can use this index to quickly locate evidence supporting specific Epithalon applications, compare study designs, and evaluate the strength of clinical evidence. Papers are sorted by relevance and citation count. There are currently 5 research papers indexed for Epithalon.

For vendor pricing, user reviews, and a complete peptide profile including mechanism of action, benefits, side effects, and regulatory status, visit the main Epithalon profile page.

Epithalon
Peptides and Ageing
Neuro Endocrinol Lett 2002 480 Animal Study
A 2002 review of pineal peptides and aging, including the Khavinson group's tetrapeptide work. A good map of how the Russian bioregulator peptide field developed and why short peptides like Epithalon and Thymogen got studied for longevity.
Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells
Bull Exp Biol Med 2003 460 Research Article
A foundational lab study reporting that Epithalon induces telomerase activity and lengthens telomeres in human cell cultures. The often-cited basis for Epithalon's anti-aging reputation — with the important caveat that it is in-vitro data, not clinical proof in humans.
Effect of the synthetic pineal peptide epitalon on spontaneous carcinogenesis in female C3H/He mice
In Vivo 2006 400 Animal Study
An animal carcinogenesis study where Epitalon slowed spontaneous tumour development in rats. Interesting gerontology data, though small and animal-only — the kind of evidence vendors sometimes over-quote as if it were human clinical data.
AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis during Neurogenesis: Possible Epigenetic Mechanism
Molecules 2020 120 Animal Study
Follow-up work from the Anisimov lab showing that Epitalon (AEDG) changes gene expression and protein synthesis in aging animal models. Helps explain proposed mechanisms for pineal peptide research and why the field kept building on the earlier telomerase findings.
Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising Properties
Int J Mol Sci 2025 20 In Vitro
Epitalon, also known as Epithalon or Epithalone, is a tetrapeptide, Ala-Glu-Asp-Gly (AEDG), which was synthesized based on the amino acids composition of Epithalamin, a bovine pineal gland extract, prior to its discovery in pineal gland polypeptide complex solution.. During the last 25 years, this compound has been extensively studied using in vitro, in vivo, and in silico methods.. The results.