Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells
Autores: Khavinson VKh, Bondarev IE, Butyugov AA
Revista
Bull Exp Biol Med
Año
2003
Citas
460
Type
Research Article
Subject
Human
Condition
Aging / Longevity
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DOI: 10.1023/a:1025493705728
Abstract
Addition of Epithalon peptide in telomerase-negative human fetal fibroblast culture induced expression of the catalytical subunit, enzymatic activity of telomerase, and telomere elongation, which can be due to reactivation of telomerase gene in somatic cells and indicates the possibility of prolonging life span of a cell population and of the whole organism.