Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells
Authors: Khavinson VKh, Bondarev IE, Butyugov AA
Journal
Bull Exp Biol Med
Year
2003
Citations
460
Type
Research Article
Subject
Human
Condition
Aging / Longevity
View Paper
DOI: 10.1023/a:1025493705728
Abstract
Addition of Epithalon peptide in telomerase-negative human fetal fibroblast culture induced expression of the catalytical subunit, enzymatic activity of telomerase, and telomere elongation, which can be due to reactivation of telomerase gene in somatic cells and indicates the possibility of prolonging life span of a cell population and of the whole organism.