LL-37: Cathelicidin-related antimicrobial peptide with pleiotropic activity

Abstract

Antimicrobial peptides (AMPs) is a large family of compounds serving as natural antibiotics, widely distributed across the organism, mainly in mucus layers.. They are designed to prevent pathogens from colonization.. Among them, defensins and cathelicidins could be found.

Hallazgos Clave

In this review, we discussed the potency of LL-37 as a therapeutic agent in four systems: immunological, respiratory, gastrointestinal and in the skin. | We analyzed the main molecular pathways dependent on human cathelicidin and related them to specific diseases. | We c

Diseño del Estudio

Review article