Investigational/Trial Medications

Discuss investigational GLP-1 drugs: retatrutide, cagrilintide, tesofensine, survodutide, mazdutide, orforglipron. Trial results and research.

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Retatrutide

Retatrutide — the triple agonist. Phase 2/3 trial results, sourcing, testing, and comparison with tirzepatide.

4 threads 13 messages
Latest:
Retatrutide Phase 3 data — what to expect
by cautious_carl 2026-08-19
Cagrilintide

Cagrilintide and CagriSema — dual therapy with semaglutide. Trial results, weight loss data, and sourcing discussion.

1 threads 3 messages
Tesofensine

Tesofensine — the forgotten weight loss drug. Mechanism, trial results, sourcing, and user experiences.

1 threads 3 messages
Latest:
Tesofensine — the forgotten weight loss drug
by watchdog_wendy 2026-08-19
Survodutide

Survodutide — dual GLP-1/glucagon agonist. Phase 3 results, MASH data, weight loss, and sourcing.

1 threads 3 messages
Latest:
Survodutide Phase 3 — 19% weight loss and MASH results
by research_rachel 2026-08-19
Mazdutide

Mazdutide — China's GLP-1/glucagon agonist. Trial data, comparison with survodutide, and availability.

1 threads 3 messages
Latest:
Mazdutide — China's answer to survodutide
by gut_issues_gary 2026-08-19
Orforglipron

Orforglipron — the first oral non-peptide GLP-1. Trial results, dosing, and comparison with injectable GLP-1s.

1 threads 3 messages
Latest:
Orforglipron — the first oral non-peptide GLP-1
by pharma_phil 2026-08-13