Week 3 on compounded semaglutide — appetite gone but energy dipping, anyone else?

2026-09-07 193 views 3 posts

Started compounded sema 3 weeks ago at 2.5mg, titrated to 5mg last week. Food noise: gone, honestly amazing. But the last few days I've had this low-grade fatigue in the afternoons that I didn't have before. Eating enough is genuinely hard. Anyone else hit the energy dip around week 3-4? Did adjusting meal timing or adding electrolytes help?

My A1C went from 9.0 to 5.8 in 6 months on tirz. My endo was shocked. The blood sugar control is honestly more important than the weight loss for me.

Following because I'm in the same boat. Week 15, 12.5mg, and the plateau is real. I'm trying to be patient but it's frustrating.