DSIP

Delta sleep-inducing peptide — promotes deep, restorative sleep

4.5
2 avis

Rating Breakdown

No Hangover or Grogginess
5.0
Deep (Delta) Sleep Promotion
4.5
Sleep Quality Improvement
4.5
Stress Reduction
4.0
Circadian Rhythm Support
3.0

Aperçu

DSIP is a naturally occurring neuropeptide that promotes delta (deep) sleep and has been studied for treatment of insomnia.

Key Information

Identity
Also Known As Delta Sleep-Inducing Peptide
Sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
CAS Number 67729-35-1
Molecular Formula C34H48N8O7
Properties
Half-Life Short (minutes)
Administration subcutaneous, intranasal
Dosage Range 100-300 mcg before sleep
Price Range $0.8–$6.0/mg
Handling & Storage
Storage Lyophilized: -20C; Reconstituted: 2-8C
Reconstitution Reconstitute with bacteriostatic water
Regulatory Status
US Status Research only
Legal Status Not FDA-approved. Available as research chemical.
Research Papers 0 indexed

Mechanism

Modulates sleep-promoting pathways in the brain, increasing delta-wave sleep without affecting overall sleep architecture.

Benefits

  • Promotes deep (delta) sleep
  • Improved sleep quality
  • No hangover effect
  • Stress reduction

Side Effects

  • Minimal reported
  • Drowsiness

Contraindications

  • None established

Evidence Summary

4 clinical studies (Bes 1992, Kaeser 1984, Monti 1987) showing improved sleep in chronic insomniacs.

Research

Clinical studies (Bes 1992, Kaeser 1984, Monti 1987) show improved sleep quality in chronic insomniacs.

Safety

Well-tolerated. No significant adverse effects in clinical studies.

Legal Status

Not FDA-approved. Available as research chemical.

No research papers

No papers have been indexed for this peptide yet.

Write a Review

Rating Breakdown

Effectiveness
4.5
Safety
4.0
Value
4.0
Overall
4.5

Based on 2 avis.

Avis

Natural sleep without drugs 2026-06-19
Jessica F.

DSIP works gently to promote deep sleep. Not a knockout drug - it normalizes sleep architecture. No dependence or withdrawal. Took about a week to notice full effects. Stress levels decreased during the day too.

Effectiveness: 4/5 Safety: 4/5 Value: 4/5
Best deep sleep I've had in years 2026-05-17
Jessica F.

DSIP gave me the deepest sleep I've had since I was a kid. Delta wave sleep increased significantly. No hangover or grogginess like sleeping pills. Wake up feeling refreshed. The stress reduction is a bonus.

Effectiveness: 5/5 Safety: 4/5 Value: 4/5