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Tesamorelin

FDA-approved GHRH analog for HIV-associated lipodystrophy

4.5
2 reviews
Rate This Peptide

Rating Breakdown

Fat Loss Support
5.0
Safety & Side Effects
4.5
GH Release Potency
4.0
IGF-1 Elevation
4.0
Muscle Preservation
4.0
Sleep Quality Improvement
4.0
Anti-Aging Effect
4.0
Cost Effectiveness
1.5

Overview

Tesamorelin is an FDA-approved GHRH analog specifically indicated for treatment of HIV-associated lipodystrophy (excess abdominal fat).

Key Information

Identity
Also Known As Egrifta
Sequence Modified GHRH(1-44) with trans-3-hexenoyl group
CAS Number 106023-15-2
Molecular Formula C221H366N74O67
Properties
Half-Life Short (30-60 minutes)
Administration subcutaneous injection
Dosage Range 2 mg daily
Price Range $1.5–$10.0/mg
Handling & Storage
Storage Refrigerated 2-8C
Reconstitution Reconstitute with provided diluent
Regulatory Status
US Status FDA-approved (Egrifta)
Research Papers 3 indexed

Mechanism

Stabilized GHRH analog that stimulates endogenous GH production, targeting visceral fat reduction.

Benefits

  • FDA-approved
  • Reduces visceral fat
  • Targets HIV lipodystrophy
  • Stimulates natural GH

Side Effects

  • Injection site reactions
  • Joint pain
  • Mild edema

Contraindications

  • Active cancer
  • Pregnancy
  • Disruption of hypothalamic-pituitary axis

Evidence Summary

FDA-approved based on Phase 3 trials showing visceral adipose tissue reduction in HIV lipodystrophy.

Research

FDA-approved based on Phase 3 trials showing significant reduction in visceral adipose tissue.

View Research

Safety

FDA-approved. Side effects include injection site reactions and joint pain.

Frequently Asked Questions About Tesamorelin

What is Tesamorelin?

Tesamorelin is a research peptide also known as Egrifta. FDA-approved GHRH analog for HIV-associated lipodystrophy It is studied for its potential therapeutic applications and is available from various research chemical vendors.

How does Tesamorelin work?

Stabilized GHRH analog that stimulates endogenous GH production, targeting visceral fat reduction.

What is the recommended dosage for Tesamorelin?

The commonly studied dosage range for Tesamorelin is 2 mg daily. Dosage protocols vary based on research objectives. Always consult published studies and start with conservative amounts. Tesamorelin should only be used in controlled research settings.

Where can I buy Tesamorelin?

PepsReview indexes Tesamorelin pricing from multiple vendors. Check the Vendors tab above for a price comparison table showing cost per milligram, purity, COA status, and stock availability. Vendor reviews from real users are available on each vendor's profile page.

Is Tesamorelin legal?

US regulatory status: FDA-approved (Egrifta). The legal status of Tesamorelin varies by jurisdiction. In most countries, it is sold as a research chemical, not for human consumption. Always verify the legal status in your country before purchasing.

What are the side effects of Tesamorelin?

Reported side effects include: Injection site reactions, Joint pain, Mild edema. Always review safety data and published studies before use.

Key Research Papers on Tesamorelin

The following peer-reviewed studies and clinical trials are indexed in our research library for Tesamorelin. Each paper links to a detailed summary with key findings, study design, and publication metadata.

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Vendor Price Comparison

Product Vendor Size Price $/mg Purity COA Stock Visit
Tesamorelin 10.0mg $45.00 $4.50 99% Third-party In Stock Visit
Tesamorelin 10mg 10.0mg $61.00 $6.10 99.8% SideChain Analytics (HPLC-MS/MS) (1d) In Stock Visit

Research

3 research papers indexed

View Research

Write a Review

Rating Breakdown

Safety
4.5
Overall
4.5
Effectiveness
4.0
Value
1.5

Based on 2 reviews.

Reviews

Eliminated my visceral fat 2026-07-29
Mike R. Top Reviewer

Tesamorelin specifically targets visceral fat. Lost 3 inches off waist in 4 months. FDA-approved for HIV lipodystrophy but works for metabolic syndrome too. GH stimulation is natural and potent.

Effectiveness: 4/5 Safety: 4/5 Value: 2/5
Effective but very expensive 2026-06-11
Mike R. Top Reviewer

Tesamorelin works well for visceral fat reduction but the cost is very high. Better results than CJC-1295 for abdominal fat. If you can afford it and have stubborn visceral fat, this is the peptide.

Effectiveness: 4/5 Safety: 5/5 Value: 1/5