Terminal signal: anti-inflammatory effects of α-melanocyte-stimulating hormone related peptides beyond the pharmacophore
Authors: Brzoska T, Böhm M, Lügering A, Loser K, Luger TA
Journal
Adv Exp Med Biol
Year
2010
Citations
320
Type
Research Article
Subject
Animal/In vitro
Condition
Inflammation
View Paper
DOI: 10.1007/978-1-4419-6354-3_8
Abstract
During the last two decades a significant number of investigations has established the fact that α-Melanocyte-stimulating hormone (α-MSH) is a potent anti-inflammatory mediator.. The anti-inflammatory effects of α-MSH can be elicited via melanocortin receptors (MC-Rs) broadly expressed in a number of tissues ranging from the central nervous system to cells of the immune system.