Bremelanotide for Treatment of Female Hypoactive Sexual Desire
Authors: Edinoff AN, Sanders NM, Lewis KB, Apgar TL, Cornett EM, et al.
Review of bremelanotide for hypoactive sexual desire disorder (HSDD) in women, a condition of persistent deficiency of sexual desire causing significant distress.
Abstract
Hypoactive sexual desire disorder (HSDD) is a persistent deficiency or absence of sexual fantasies and desire resulting in significant distress or interpersonal difficulty.. Women with this disorder may display a lack of motivation for sexual activity, reduced responsiveness to erotic cues, a loss of interest during sexual activity, and avoidance of situations that could lead to sexual activity...
Key Findings
Hypoactive sexual desire disorder (HSDD) is a persistent deficiency or absence of sexual fantasies and desire resulting in significant distress or interpersonal difficulty. | Women with this disorder may display a lack of motivation for sexual activity, reduced responsiveness to erotic cues, a loss of interest during sexual activity, and avoidance of situations that could ...Study Design
Research studyMore PT-141 (Bremelanotide) Research Papers
Additional peer-reviewed studies and clinical trials indexed for PT-141 (Bremelanotide) on PepsReview:
- PT-141 Palatin — Curr Opin Investig Drugs, 2004 (440 citations)
- An effect on the subjective sexual response in premenopausal women with sexual arousal disorder by bremelanotide (PT-141), a melanocortin receptor agonist — J Sex Med, 2006 (400 citations)
- Bremelanotide: New Drug Approved for Treating Hypoactive Sexual Desire Disorder — Ann Pharmacother, 2020 (120 citations)
- Hypoactive Sexual Desire Disorder in Women: Physiology, Assessment, Diagnosis, and Treatment — J Midwifery Womens Health, 2021 (100 citations)
About This PT-141 (Bremelanotide) Research Paper
This study is part of PepsReview's indexed research library for PT-141 (Bremelanotide). We systematically index peer-reviewed publications, clinical trial results, and scientific studies related to PT-141 (Bremelanotide) to provide researchers and clinicians with a centralized, searchable database of evidence. Each paper in our index includes metadata such as journal name, publication year, citation count, study type, and condition studied, along with key findings and study design summaries where available.
PT-141 (Bremelanotide) is classified in our Sexual health / Libido category. FDA-approved for female sexual arousal disorder For a complete list of research papers on PT-141 (Bremelanotide), visit the research index page. To compare vendor pricing and read user reviews, visit the main PT-141 (Bremelanotide) profile page.
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PT-141 (Bremelanotide) has been the subject of growing scientific interest, with researchers investigating its pharmacological properties, therapeutic potential, and safety profile across multiple study designs. The research landscape for PT-141 (Bremelanotide) includes preclinical in vitro and animal model studies that elucidate its mechanism of action, Phase I clinical trials assessing safety and pharmacokinetics in human subjects, and larger Phase II and Phase III trials evaluating efficacy in target populations. Published studies vary in design — some are randomized controlled trials with placebo groups, others are open-label dose-escalation studies, and many are retrospective analyses of real-world data from clinics and compounding pharmacies.
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