LL-37
Cathelicidin humano — peptídeo antimicrobiano de amplo espectro
Visão Geral
LL-37 é o único peptídeo antimicrobiano catelicidina humano, fornecendo defesa de amplo espectro contra bactérias, vírus e fungos.
Key Information
Mecanismo
Rompe as membranas microbianas e modula o sistema imunológico. Efeitos antimicrobianos + imunomoduladores diretos.
Benefits
- Antimicrobiano de amplo espectro
- Atividade antibiofilme
- Modulação imunológica
- Suporte à cicatrização de feridas
Side Effects
- Potencial de resistência em doses subterapêuticas
- Irritação em altas concentrações
Contraindications
- None established
Evidence Summary
Estudos demonstram eficácia contra bactérias, biofilmes e modulação imunológica.
Research
Estudos demonstram eficácia contra infecções bacterianas, biofilmes, e como modulador imunológico em infecções crônicas.
Ver InvestigaciónSafety
Geralmente bem tolerado. Potencial de resistência em doses subterapêuticas.
Frequently Asked Questions About LL-37
What is LL-37?
LL-37 is a research peptide also known as Cathelicidin; hCAP-18. Cathelicidin humano — peptídeo antimicrobiano de amplo espectro It is studied for its potential therapeutic applications and is available from various research chemical vendors.
How does LL-37 work?
Rompe as membranas microbianas e modula o sistema imunológico. Efeitos antimicrobianos + imunomoduladores diretos.
What is the recommended dosage for LL-37?
The commonly studied dosage range for LL-37 is Varies by application. Dosage protocols vary based on research objectives. Always consult published studies and start with conservative amounts. LL-37 should only be used in controlled research settings.
Where can I buy LL-37?
PepsReview indexes LL-37 pricing from multiple vendors. Check the Vendors tab above for a price comparison table showing cost per milligram, purity, COA status, and stock availability. Vendor reviews from real users are available on each vendor's profile page.
Is LL-37 legal?
US regulatory status: Research only. The legal status of LL-37 varies by jurisdiction. In most countries, it is sold as a research chemical, not for human consumption. Always verify the legal status in your country before purchasing.
What are the side effects of LL-37?
Reported side effects include: Potencial de resistência em doses subterapêuticas, Irritação em altas concentrações. Always review safety data and published studies before use.
Key Research Papers on LL-37
The following peer-reviewed studies and clinical trials are indexed in our research library for LL-37. Each paper links to a detailed summary with key findings, study design, and publication metadata.
- LL-37: Cathelicidin-related antimicrobial peptide with pleiotropic activity — Pharmacol Rep, 2016 (200 citations)
- Design of Antimicrobial Peptides: Progress Made with Human Cathelicidin LL-37 — Adv Exp Med Biol, 2019 (140 citations)
- LL-37 Triggers Antimicrobial Activity in Human Platelets — Int J Mol Sci, 2023 (60 citations)
- The LL-37 domain: A clue to cathelicidin immunomodulatory response? — Peptides, 2023 (60 citations)
- Antimicrobial Peptides of the Cathelicidin Family: Focus on LL-37 and Its Modifications — Int J Mol Sci, 2025 (20 citations)
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Rating Breakdown
Based on 2 avaliações.
Avaliações
LL-37 cleared a chronic bacterial infection that antibiotics couldn't touch. The broad-spectrum antimicrobial activity is impressive. Anti-biofilm properties make it effective against resistant bacteria. Wound healing also accelerated.
LL-37 is a remarkable immune weapon. Fought off a stubborn sinus infection in days. The antimicrobial and antiviral defense is broad-spectrum. Be careful with dosing - too much can cause inflammation.