LL-37
Human cathelicidin — broad-spectrum antimicrobial peptide
Overview
LL-37 is the only human cathelicidin antimicrobial peptide, providing broad-spectrum defense against bacteria, viruses, and fungi.
Key Information
Mechanism
Disrupts microbial membranes and modulates the immune system. Direct antimicrobial + immunomodulatory effects.
Benefits
- Broad-spectrum antimicrobial
- Anti-biofilm activity
- Immune modulation
- Wound healing support
Side Effects
- Potential for resistance at sub-therapeutic doses
- Irritation at high concentrations
Contraindications
- None established
Evidence Summary
Studies show efficacy against bacteria, biofilms, and immune modulation.
Research
Studies show efficacy against bacterial infections, biofilms, and as an immune modulator in chronic infections.
Safety
Generally well-tolerated. Potential for resistance at sub-therapeutic doses.
Legal Status
Not FDA-approved. Available as research chemical.
No research papers
No papers have been indexed for this peptide yet.
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Rating Breakdown
Reviews
LL-37 cleared a chronic bacterial infection that antibiotics couldn't touch. The broad-spectrum antimicrobial activity is impressive. Anti-biofilm properties make it effective against resistant bacteria. Wound healing also accelerated.
LL-37 is a remarkable immune weapon. Fought off a stubborn sinus infection in days. The antimicrobial and antiviral defense is broad-spectrum. Be careful with dosing - too much can cause inflammation.