LL-37
Cathelicidin humain — peptide antimicrobien à large spectre
Aperçu
LL-37 est la seule cathélicidine antimicrobienne humaine, offrant une défense à large spectre contre les bactéries, les virus et les champignons.
Key Information
Mechanism
Perturbe les membranes microbiennes et module le système immunitaire. Effets antimicrobiens + immunomodulateurs directs.
Benefits
- Antimicrobien à large spectre
- Activité anti-biofilm
- Modulation immunitaire
- Soutien de la cicatrisation
Side Effects
- Risque de résistance à des doses sous-thérapeutiques
- Irritation à des concentrations élevées
Contraindications
- None established
Evidence Summary
Les études montrent une efficacité contre les bactéries, les biofilms et la modulation immunitaire.
Research
Les études montrent une efficacité contre les infections bactériennes, les biofilms, ainsi qu'en tant que modulateur immunitaire dans les infections chroniques.
View ResearchSafety
Généralement bien toléré. Risque de résistance à des doses sous-thérapeutiques.
Frequently Asked Questions About LL-37
What is LL-37?
LL-37 is a research peptide also known as Cathelicidin; hCAP-18. Cathelicidin humain — peptide antimicrobien à large spectre It is studied for its potential therapeutic applications and is available from various research chemical vendors.
How does LL-37 work?
Perturbe les membranes microbiennes et module le système immunitaire. Effets antimicrobiens + immunomodulateurs directs.
What is the recommended dosage for LL-37?
The commonly studied dosage range for LL-37 is Varies by application. Dosage protocols vary based on research objectives. Always consult published studies and start with conservative amounts. LL-37 should only be used in controlled research settings.
Where can I buy LL-37?
PepsReview indexes LL-37 pricing from multiple vendors. Check the Vendors tab above for a price comparison table showing cost per milligram, purity, COA status, and stock availability. Vendor reviews from real users are available on each vendor's profile page.
Is LL-37 legal?
US regulatory status: Research only. The legal status of LL-37 varies by jurisdiction. In most countries, it is sold as a research chemical, not for human consumption. Always verify the legal status in your country before purchasing.
What are the side effects of LL-37?
Reported side effects include: Risque de résistance à des doses sous-thérapeutiques, Irritation à des concentrations élevées. Always review safety data and published studies before use.
Key Research Papers on LL-37
The following peer-reviewed studies and clinical trials are indexed in our research library for LL-37. Each paper links to a detailed summary with key findings, study design, and publication metadata.
- LL-37: Cathelicidin-related antimicrobial peptide with pleiotropic activity — Pharmacol Rep, 2016 (200 citations)
- Design of Antimicrobial Peptides: Progress Made with Human Cathelicidin LL-37 — Adv Exp Med Biol, 2019 (140 citations)
- LL-37 Triggers Antimicrobial Activity in Human Platelets — Int J Mol Sci, 2023 (60 citations)
- The LL-37 domain: A clue to cathelicidin immunomodulatory response? — Peptides, 2023 (60 citations)
- Antimicrobial Peptides of the Cathelicidin Family: Focus on LL-37 and Its Modifications — Int J Mol Sci, 2025 (20 citations)
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Rating Breakdown
Based on 2 avis.
Avis
LL-37 cleared a chronic bacterial infection that antibiotics couldn't touch. The broad-spectrum antimicrobial activity is impressive. Anti-biofilm properties make it effective against resistant bacteria. Wound healing also accelerated.
LL-37 is a remarkable immune weapon. Fought off a stubborn sinus infection in days. The antimicrobial and antiviral defense is broad-spectrum. Be careful with dosing - too much can cause inflammation.