Research: LL-37

Human cathelicidin — broad-spectrum antimicrobial peptide

LL-37 Research Papers & Clinical Studies

LL-37 is a peptide studied for its potential therapeutic effects. Human cathelicidin — broad-spectrum antimicrobial peptide This page indexes all published research papers, clinical trials, and scientific studies related to LL-37 that are available in the PepsReview research library. Each paper includes metadata such as journal name, publication year, citation count, study type, and a summary of key findings. Where available, we provide direct links to the original publication and DOI references.

Researchers can use this index to quickly locate evidence supporting specific LL-37 applications, compare study designs, and evaluate the strength of clinical evidence. Papers are sorted by relevance and citation count. There are currently 5 research papers indexed for LL-37.

For vendor pricing, user reviews, and a complete peptide profile including mechanism of action, benefits, side effects, and regulatory status, visit the main LL-37 profile page.

LL-37
LL-37: Cathelicidin-related antimicrobial peptide with pleiotropic activity
Pharmacol Rep 2016 200 Review
A broad 2016 review of LL-37 as a pleiotropic host-defence peptide: antimicrobial, immunomodulatory, and wound-healing roles. A solid starting reference for anyone researching cathelicidin biology.
Design of Antimicrobial Peptides: Progress Made with Human Cathelicidin LL-37
Adv Exp Med Biol 2019 140 Research Article
A design-oriented review of antimicrobial peptide engineering using human cathelicidin LL-37 as a template. Covers how researchers derive shorter, more selective peptides from LL-37's sequence — the practical base for synthetic peptide antibiotics.
LL-37 Triggers Antimicrobial Activity in Human Platelets
Int J Mol Sci 2023 60 Research Article
A 2023 study showing LL-37 triggers antimicrobial activity in human platelets — an unexpected link between coagulation and innate immunity. Adds to the picture of cathelicidin as a broadly active host-defence peptide rather than a simple antibiotic.
The LL-37 domain: A clue to cathelicidin immunomodulatory response?
Peptides 2023 60 Review
A review exploring how the LL-37 structure relates to its immunomodulatory roles. Helps explain why cathelicidin research keeps returning to sequence and folding — the same peptide can kill bacteria, signal receptors, and modulate inflammation.
Antimicrobial Peptides of the Cathelicidin Family: Focus on LL-37 and Its Modifications
Int J Mol Sci 2025 20 Research Article
Cathelicidins are a family of antimicrobial peptides (AMPs) with broad-spectrum activity and immunomodulatory functions.. Among them, the only human cathelicidin LL-37 has garnered significant interest due to its potent antimicrobial, antiviral, antifungal, antiparasitic, and antitumor properties.. However, the clinical application of LL-37 is hindered by several limitations, including low.