Thymosin alpha 1 treatment for patients with sepsis

Authors: Pei F, Guan X, Wu J

Journal
Expert Opin Biol Ther
Year
2018
Citations
160
Type
Review
Subject
Human
Condition
Immune Modulation / Hepatitis
View Paper DOI: 10.1080/14712598.2018.1484104

Abstract

Sepsis is a life-threatening organ dysfunction caused by host immune response to infection.. In this regard, modifying host immune response may help to eliminate systemic infection and restore organ function.. Thymosin alpha 1 (Tα1), acting as an immune modulator, exerts great biological influence in activating and restoring the dysregulated immune response for patients with sepsis.

Key Findings

In previous studies, single or combined treatment with Tα1 reduced the mortality rate of sepsis, improved the exp

Study Design

Review article