Thymosin alpha-1 treatment in chronic hepatitis B

Authors: Wu X, Jia J, You H

Journal
Expert Opin Biol Ther
Year
2015
Citations
220
Type
Review
Subject
Human
Condition
Immune Modulation / Hepatitis
View Paper DOI: 10.1517/14712598.2015.1007948

Abstract

Stimulating a successful host immune response may be a promising helpful therapy to achieve elimination of hepatitis B virus (HBV) infection in chronic hepatitis B (CHB).. Thymosin α-1 (Tα-1), as an immunomodulatory agent, can enhance T-cell response in CHB patients and has been widely studied either alone or in combination with nucleos(t)ide analogs.. This editorial reviews these.

Key Findings

In CHB, Tα-1monotherapy is effectiv

Study Design

Randomized controlled trial