Semax

Cognitive enhancer — improves focus, memory, and mental clarity

4.5
2 avis

Rating Breakdown

Cognitive Enhancement
5.0
Memory & Focus
5.0
No Sedation or Impairment
5.0
No Addiction or Withdrawal
5.0
Neuroprotection
4.5
Mood & BDNF Boost
4.0
Anxiolytic Effect
3.0
Immune Modulation
2.0

Aperçu

Semax is a synthetic peptide derived from ACTH that has cognitive-enhancing and neuroprotective effects without hormonal activity.

Key Information

Identity
Also Known As ACTH(4-7)-Pro-Gly-Pro
Sequence Met-Glu-His-Phe-Pro-Gly-Pro
CAS Number 154101-31-0
Molecular Formula C37H51N9O9
Properties
Half-Life Short (minutes)
Administration intranasal
Dosage Range 300-600 mcg daily
Price Range $1.0–$7.0/mg
Handling & Storage
Storage Lyophilized: -20C; Reconstituted: 2-8C
Reconstitution Reconstitute with bacteriostatic water
Regulatory Status
US Status Approved in Russia; research elsewhere
Legal Status Approved in Russia. Not FDA-approved. Available as research chemical.
Research Papers 0 indexed

Mechanism

Increases BDNF and NGF in the brain, enhances monoamine neurotransmission, and provides neuroprotection.

Benefits

  • Cognitive enhancement
  • Neuroprotective
  • Memory improvement
  • Increased BDNF and NGF
  • Post-stroke recovery

Side Effects

  • Minimal reported
  • No significant adverse effects in 30+ years

Contraindications

  • None established

Evidence Summary

30+ years of Russian clinical use. Studies show improved cognitive performance and neuroprotection.

Research

Russian clinical studies show improved cognitive performance, attention, and memory in healthy and post-stroke patients.

Safety

Excellent safety profile. No significant adverse effects reported in 30+ years of Russian use.

Legal Status

Approved in Russia. Not FDA-approved. Available as research chemical.

No research papers

No papers have been indexed for this peptide yet.

Write a Review

Rating Breakdown

Effectiveness
5.0
Safety
5.0
Value
4.0
Overall
4.5

Based on 2 avis.

Avis

Great for studying and focus 2026-06-03
Daniel G.

Used Semax during exam season. Focus was laser-sharp for 4-6 hours per dose. Memory retention improved. Slight anxiety increase compared to Selank but the cognitive boost is stronger. Nasal administration works fast.

Effectiveness: 5/5 Safety: 5/5 Value: 4/5
Sharper than modafinil 2026-05-01
Daniel G.

Semax gives clean cognitive enhancement without jitters. Focus and memory improved within days. BDNF and NGF increase is real - learning new skills feels easier. Post-stroke recovery data is impressive.

Effectiveness: 5/5 Safety: 5/5 Value: 4/5