Epithalon
Telomerase activator — anti-aging and longevity peptide
Overview
Epithalon is a synthetic tetrapeptide that activates telomerase, potentially slowing cellular aging by preserving telomere length.
Key Information
Mechanism
Activates telomerase enzyme, which lengthens telomeres at chromosome ends, potentially reversing cellular senescence.
Benefits
- Telomerase activation
- Potential lifespan extension
- Improved biomarkers of aging
- Immune system support
Side Effects
- Minimal reported
Contraindications
- None established
Evidence Summary
Russian studies show lifespan extension in animals and improved aging biomarkers in humans.
Research
Russian studies show lifespan extension in animal models and improved biomarkers of aging in human trials.
View ResearchSafety
Well-tolerated. No significant adverse effects reported.
Frequently Asked Questions About Epithalon
What is Epithalon?
Epithalon is a research peptide also known as Epitalon; Epithalamin. Telomerase activator — anti-aging and longevity peptide It is studied for its potential therapeutic applications and is available from various research chemical vendors.
How does Epithalon work?
Activates telomerase enzyme, which lengthens telomeres at chromosome ends, potentially reversing cellular senescence.
What is the recommended dosage for Epithalon?
The commonly studied dosage range for Epithalon is 5-10 mg per course (5-10 days). Dosage protocols vary based on research objectives. Always consult published studies and start with conservative amounts. Epithalon should only be used in controlled research settings.
Where can I buy Epithalon?
PepsReview indexes Epithalon pricing from multiple vendors. Check the Vendors tab above for a price comparison table showing cost per milligram, purity, COA status, and stock availability. Vendor reviews from real users are available on each vendor's profile page.
Is Epithalon legal?
US regulatory status: Research only. The legal status of Epithalon varies by jurisdiction. In most countries, it is sold as a research chemical, not for human consumption. Always verify the legal status in your country before purchasing.
What are the side effects of Epithalon?
Reported side effects include: Minimal reported. Always review safety data and published studies before use.
Key Research Papers on Epithalon
The following peer-reviewed studies and clinical trials are indexed in our research library for Epithalon. Each paper links to a detailed summary with key findings, study design, and publication metadata.
- Peptides and Ageing — Neuro Endocrinol Lett, 2002 (480 citations)
- Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells — Bull Exp Biol Med, 2003 (460 citations)
- Effect of the synthetic pineal peptide epitalon on spontaneous carcinogenesis in female C3H/He mice — In Vivo, 2006 (400 citations)
- AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis during Neurogenesis: Possible Epigenetic Mechanism — Molecules, 2020 (120 citations)
- Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising Properties — Int J Mol Sci, 2025 (20 citations)
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Rating Breakdown
Based on 2 reviews.
Reviews
Epithalon improved my sleep architecture - deeper, more restful sleep. Telomerase activation is the main draw. Been using for 6 months. Biomarkers of aging improved slightly. Very safe with no side effects.
Epithalon is a long game. No instant effects but after 6 months my immune system is stronger - haven't been sick once. Sleep is noticeably deeper. The telomere research is compelling for longevity.