Not Sure Which Protocol Is Right for You?

Take our 3-minute quiz and get a personalized peptide protocol with exact dosages and cycling — tailored to your goals and body.

✓ Free ✓ Private ✓ Science-backed
Start the Quiz →

SS-31 (Elamipretide)

Mitochondria-targeted peptide — restores cellular energy production

4.5
2 reviews
Rate This Peptide

Rating Breakdown

Mitochondrial Function
5.0
Oxidative Stress Reduction
5.0
Cardioprotective Effect
5.0
Aging Biomarker Improvement
4.0
Safety & Side Effects
4.0
Immune System Support
3.0
Telomere & Cellular Aging
2.5

Overview

SS-31 (Elamipretide) is a mitochondria-targeted peptide that selectively concentrates in the inner mitochondrial membrane to restore mitochondrial function.

Key Information

Identity
Also Known As Elamipretide; Bendavia
Sequence D-Arg-Dmt-Lys-Phe-NH2
CAS Number 736959-44-7
Molecular Formula C32H52N6O7
Properties
Half-Life Short (hours)
Administration subcutaneous injection
Dosage Range Varies by indication (clinical trials)
Price Range $1.5–$12.0/mg
Handling & Storage
Storage Lyophilized: -20C; Reconstituted: 2-8C
Reconstitution Reconstitute with bacteriostatic water
Regulatory Status
US Status Investigational (Phase 3)
Research Papers 4 indexed

Mechanism

Binds to cardiolipin in the inner mitochondrial membrane, restoring electron transport chain function and reducing oxidative stress.

Benefits

  • Restores mitochondrial function
  • Reduces oxidative stress
  • Cardioprotective
  • Potential anti-aging

Side Effects

  • Minimal reported in trials
  • Mild injection site reactions

Contraindications

  • None established

Evidence Summary

Phase 2 trials show improved mitochondrial function in cardiomyopathy and kidney disease.

Research

Phase 2 trials show improvement in mitochondrial function, with applications in cardiomyopathy, kidney disease, and aging.

View Research

Safety

Well-tolerated in Phase 2 trials. Currently in Phase 3.

Frequently Asked Questions About SS-31 (Elamipretide)

What is SS-31 (Elamipretide)?

SS-31 (Elamipretide) is a research peptide also known as Elamipretide; Bendavia. Mitochondria-targeted peptide — restores cellular energy production It is studied for its potential therapeutic applications and is available from various research chemical vendors.

How does SS-31 (Elamipretide) work?

Binds to cardiolipin in the inner mitochondrial membrane, restoring electron transport chain function and reducing oxidative stress.

What is the recommended dosage for SS-31 (Elamipretide)?

The commonly studied dosage range for SS-31 (Elamipretide) is Varies by indication (clinical trials). Dosage protocols vary based on research objectives. Always consult published studies and start with conservative amounts. SS-31 (Elamipretide) should only be used in controlled research settings.

Where can I buy SS-31 (Elamipretide)?

PepsReview indexes SS-31 (Elamipretide) pricing from multiple vendors. Check the Vendors tab above for a price comparison table showing cost per milligram, purity, COA status, and stock availability. Vendor reviews from real users are available on each vendor's profile page.

Is SS-31 (Elamipretide) legal?

US regulatory status: Investigational (Phase 3). The legal status of SS-31 (Elamipretide) varies by jurisdiction. In most countries, it is sold as a research chemical, not for human consumption. Always verify the legal status in your country before purchasing.

What are the side effects of SS-31 (Elamipretide)?

Reported side effects include: Minimal reported in trials, Mild injection site reactions. Always review safety data and published studies before use.

Key Research Papers on SS-31 (Elamipretide)

The following peer-reviewed studies and clinical trials are indexed in our research library for SS-31 (Elamipretide). Each paper links to a detailed summary with key findings, study design, and publication metadata.

Related Anti-aging / Longevity Peptides

Other peptides in the anti-aging / longevity category that may be of interest for comparative research:

Epithalon Telomerase activator — anti-aging and longevity peptide KPV Anti-inflammatory tripeptide — gut healing and immune modulation MOTS-c Mitochondrial-derived peptide studied for metabolic health, insulin sensitivity, exercise capacity, and cellular energy support. Thymosin Alpha-1 Immune modulator — enhances T-cell function and fights infection

Vendor Price Comparison

Product Vendor Size Price $/mg Purity COA Stock Visit
SS-31 10mg
Volta Peptides
10.0mg $34.00 $3.40 99.8% SideChain Analytics (HPLC-MS/MS) (1d) In Stock Visit

Research

4 research papers indexed

View Research

Write a Review

Rating Breakdown

Overall
4.5
Safety
4.0
Value
4.0
Effectiveness
2.5

Based on 2 reviews.

Reviews

Mitochondrial game changer 2026-05-26
Jenny K. Top Reviewer

SS-31 restored my energy levels dramatically. Chronic fatigue improved within weeks. The mitochondrial function improvement is real - I can feel the difference in cellular energy. Cardioprotective effects are well-documented.

Effectiveness: 2/5 Safety: 4/5 Value: 4/5
Best peptide for mitochondrial health 2026-05-21
Mike L. Top Reviewer

SS-31 is unmatched for mitochondrial dysfunction. Energy increased, exercise tolerance improved, oxidative stress markers down. The cardiac research is impressive. Expensive but worth it for serious longevity protocols.

Effectiveness: 3/5 Safety: 4/5 Value: 4/5

Community Discussions on SS-31 (Elamipretide)

Join the conversation in our peptide community forum. Real users share their ss-31 (elamipretide) experiences, dosing schedules, results, and tips.

Visit the community forum